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Application of copper pyrrolidone carboxylate

    Copper pyrrolidone carboxylate can be used as intermediate in pharmaceutical synthesis. It can be used in laboratory research and development process and chemical pharmaceutical synthesis process. If inhaling copper pyrrolidone carboxylate, remove person to fresh air; In case of skin contact, take off contaminated clothing, wash skin thoroughly with soapy water and clean water, if discomfort, seek medical advice; In case of eye contact, separate eyelid, rinse with running water or normal saline, and seek medical attention immediately; If ingested, gargle immediately, do not induce vomiting, should seek medical attention immediately.
    1) Prepare a skin repair emulsion, dissolve 0.004-0.2-g metallothionein and 0.002-0.04-g recombinant human epidermal growth factor in pure water, and add 0.02-5-g proanthocyanidin, 0.01-5-g vitamin C and 0.01-4-g vitamin E. The first solution was obtained by adding 0.02-5-g allantoin and 0.04-6-g Seabuckthorn seed oil. Sodium 5-100-g pyrrolidone carboxylate and copper 5-100-g pyrrolidone carboxylate were dissolved in pure water. The second solution was obtained by adding 5-100-g octadecyl alcohol, 5-80-g isopropyl myristate and 0.1-10-g hydroxypropyl methylcellulose. The third solution is obtained by dissolving 0.1-5-g antiseptic with pure water. The first, second and third solutions are mixed, then filled with pure water to 1000-g, and then mixed, filtered and filled. Shorten the time of wound epithelialization.
    2) A skin repair composition was prepared by dissolving metallothionein 0.004-0.2g and recombinant human epidermal growth factor 0.002-0.04g in pure water with 400-500g, filling and lyophilizing after filtration to obtain component A; Proanthocyanidin 0.02-5g, vitamin C0.01-5g and vitamin E0.01-4g were dissolved in pure water 190-210g, allantoin 0.02-5g and sea buckthorn seed oil 0.04-6g were added to dissolve the first solution. Dissolve 5-100g sodium pyrrolidone carboxylate and 5-100g copper pyrrolidone carboxylate in pure water 200-500g, add 5-100-g octadecyl alcohol and 5-80g isopropyl myristate to dissolve the second solution; Dissolve the preservative 0.1-5g with pure water 190-110g to obtain the third solution; The first, second and third solutions were mixed, filtered and filled to obtain B component.
    3) To prepare a liquid dressing for wound healing, the steps are as follows: dissolve 0.004-0.4g metallothionein with pure water in the state of agitation, then add 0.01-4g vitamin C and stir until dissolved to obtain the first solution; The second solution was obtained by dissolving 0.02-2g sodium alginate in stirred state with pure water. First, add the second solution to the first solution or the first solution to the second solution and stir and control the agitation time, then add 5-100g copper pyrrolidone carboxylate and continue to stir and control the agitation time, and then use pure water to fix the volume to 1000-g, to obtain the wound healing liquid dressing. Shorten the time of wound epithelialization; Reflect the ideal recovery effect of the wound skin; It is beneficial to enhance the life span of the body and the anti-stress ability and immunity to the external environment. It is easy to absorb the wound effusion, shorten the wound healing time and reduce the chance of wound infection.

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